As announced by Microsoft on the 18th March the hotfix Package 1 for App-V 5.0 Sp3 is now available
The following issues were addressed:
Issue 1: Virtualized Adobe Acrobat running through an App-V Client on Windows 7 crashes or stops responding because of DLL issues
Virtualized Adobe Acrobat running on Windows 7 may crash or stop responding because of an interoperability issue between App-V and Adobe. This issue causes App-V to sometimes load multiple copies of the same DLL from different locations. This, in turn, causes the virtual Adobe Acrobat application to crash or stop responding when certain operations are performed. This issue is fixed in this hotfix package.
Issue 2: Stop error is triggered by DLL issues when an App-V Client tries to load Adobe Acrobat packages
Some products, such as Adobe Acrobat, use DLLs that have file name extensions other than .dll. When an App-V Client loads virtualized packages of these applications, it does not recognize these files as DLLs and does not exclude them from the copy-on-write subsystem. A Stop error may occur when a package is run that uses these DLLs.
The hotfix package is available as download here:
https://support.microsoft.com/en-us/kb/3039022
